WebApplication: CCR4 Antagonist is a diaminoquinazoline compound and potent antagonist of CCR4 CAS Number: 864289-85-0 Purity: ≥97% Molecular Weight: 467.66 Molecular Formula: C 27 H 41 N 5 O 2 For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. * Refer to Certificate of Analysis for lot specific data (including water content). WebINCB 3284 is a potent, selective, and orally bioavailable antagonist of monocyte chemotactic protein- 1 binding to CCR2 (IC 50 = 3.7 nM). 1 For comparison, it has no significant inhibitor action at over 50 ion channels, transporters, GPCRs, and other chemokine receptors when tested at a concentration of 1 μM. 1 INCB 3284 inhibits chemotaxis in …

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WebINCB 3284 dimesylate is a potent, selective hCCR2 antagonist. Exhibits potent antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity … WebINCB 3284 dimesylate exhibits potenct antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity (IC50 values are 3.7 and 4.7 nM … iowa hawkeye bowl prediction 2021

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WebIn Vitro INCB 3284 dimesylate is a pentent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC50 of 3.7 nM. INCB 3284 also causes an IC50 of 4.7 nM in antagonism of chemotaxis activity, an IC50 of 84 μM in inhibition of the hERG potassium current. However, INCB ... WebInxight Drugs. Discovery of INCB3284, a Potent, Selective, and Orally Bioavailable hCCR2 Antagonist. Klotho gene deficiency causes salt-sensitive hypertension via monocyte … Web丁香通为您提供 生物素标记Fab2片商品详情介绍：价格：询价，货号： GtxMu-003-J2BIO，CAS号：详见说明书，品牌：慧嘉生物，详见丁香通 生物素标记Fab2片商品详情页； opelousas la sheriff\u0027s office