WebHere we show that durable neoantigen-specific immunity is regulated by mRNA N 6 -methyadenosine (m 6 A) methylation through the m 6 A-binding protein YTHDF1 5. In contrast to wild-type mice, Ythdf1-deficient mice show an elevated antigen-specific CD8 + T cell antitumour response. Loss of YTHDF1 in classical dendritic cells enhanced the cross ... http://www.icsb.tsinghua.edu.cn/english.php?c=show&id=764
Loop Chen Dong
WebSep 17, 2024 · Growing evidence indicates the vital role of lipid metabolites in innate immunity. The lipid lysophosphatidic acid (LPA) concentrations are enhanced in patients upon HCV or SARS-CoV-2 infection, but the function of LPA and its receptors in innate immunity is largely unknown. WebPathogen-associated T follicular helper cell plasticity is critical in anti-viral immunity Sci China Life Sci. 2024 Jun;65 ... Hong Tang 4 5 6 , Xiaohu Wang 1 , Chen Dong 7 8 Affiliations 1 Institute for Immunology, Tsinghua University, Beijing, 100084, China. 2 Discovery Immunology, Bristol Myers Squibb ... buckeye property management toledo ohio
Loop Chen Dong
WebNov 19, 2024 · Immunity. 2024 Nov 19;51(5):826-839.e5. doi: 10.1016/j.immuni.2024.10.006. ... Xindong Liu 3 , Chen Dong 4 Affiliations 1 College of Life Science and Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, Peking University, Beijing, China; Institute for Immunology ... WebImmune tolerance and tumor immunity. Chinese. Home; About us. About us. Founded in 2015, the Advanced Innovation Center for Structural Biology of Tsinghua University is now headed by the distinguished structural biologist, Prof. Yigong Shi. ... Chen Dong Ph.D. 2024 Highly Cited Researcher, Clarivate Analytics 2016 Highly Cited Researcher ... WebJan 18, 2008 · The precise biochemical function of STAT3 is unclear at this point. Although STAT3 has been shown to bind to the Il17 gene promoter (Chen et al., 2006), STAT3 appears to control more than just IL-17 gene expression (Yang et al., 2007). It is likely that, STAT3, similar to STAT1 and STAT6, functions in regulation of lineage-specific master ... buckeye provider adjustment request form